Follicle stimulating hormone (FSH), also known as follicle stimulating hormone, is secreted by the pituitary gland. In men, its function is to promote the maturation of testicular seminiferous tubules and spermatogenesis; In women, the function of FSH is to promote the development and maturation of follicles, and cooperate with luteinizing hormone (LH) to promote the secretion of estrogen and ovulation of mature follicles, and participate in the formation of normal menstruation. Its production is controlled by hypothalamic gonadotropin-releasing hormone (GnRH) and feedback regulated by ovarian estrogen (E2). FSH plays a decisive role in the sexual and reproductive functions of both sexes.
Through the determination of FSH, we can understand the pituitary endocrine function, but also indirectly understand the functional status of hypothalamus and ovary. This is very helpful for the differential diagnosis of pituitary or hypothalamic amenorrhea.