Treponema pallidum(TP)

Treponema pallidum is known as Treponema pallidum because it is transparent and not easy to stain. It can be dyed pink with Giemsa. It is a dense spirochete, soft and slender spirochete, shaped like a metal shaving, about 6-12 in length μ m. Width 0.09-0.18 μ m. There are 8-12 neat and uniform helices.

Syphilis antibody detection is divided into non Treponema pallidum antigen serological test and Treponema pallidum antigen serological test.

1、Non Treponema pallidum antigen serological test: mainly including venereal disease research laboratory test (VDRL), unheated serum reagin test (USR), rapid plasma reagin ring card test (RPR) and toluidine red unheated serum test (trust).

2、Treponema pallidum antigen serological test: commonly used mainly include Treponema pallidum particle agglutination test (TPPA), Treponema pallidum hemagglutination test (TPHA), syphilis enzyme-linked immunosorbent assay (ELISA), chemiluminescence immunoassay (CLIA), and syphilis immunochromatography rapid detection of syphilis (RT), fluorescent Treponema antibody absorption test (FTA-ABS), Treponema pallidum western blot test (WB).Tp15, TP17 and TP47 are outer membrane lipoproteins of Treponema pallidum.