Mouse anti human

The IgG antibody molecule is composed of 2 heavy chains and 2 light chains connected by disulfide bonds. The basic principle of human mouse chimeric antibody is to isolate and identify rearranged functional murine VL (light chain variable region) and VH (heavy chain variable region) from the genome of hybridoma cells secreting a certain murine monoclonal antibody. After genetic recombination, they are spliced with human Cl (light chain constant region) and CH (heavy chain constant region) genes in a certain way, cloned into expression vectors to construct murine / human light chain gene expression vectors, and transferred into appropriate host cells for expression to prepare specific chimeric antibodies.

Mouse anti human IgM (monoclonal antibody) this product uses mouse ascites with high titer antibody as raw material, and is purified by immunoaffinity chromatography to remove the impurity antibody, and is purified by immunoaffinity chromatography to make anti human IgM with high purity (> 95%) and high activity（ μ Chain specific) monoclonal antibodies.