Cocaine can damage the digestive system, immune system, cardiovascular system and genitourinary system, especially as a dose-dependent hepatotoxin, which can lead to hepatocyte necrosis. However, unlike other drugs, a small amount of cocaine or cocaine containing substances can indeed eliminate fatigue and improve mood (there is still no accurate data on the specific dose and the interval fluctuates greatly). The research believes that it can block human nerve conduction, produce local anesthesia, and stimulate the cerebral cortex and excite the central nerve by enhancing the activity of chemicals (such as dopamine) in the human body. Show high mood, active, and even aggressive. Further research also confirmed that the structure and function of the corresponding brain regions would change after cocaine use.