N-terminal pro brain natriuretic peptide is a kind of laboratory test in medicine. It is an important indicator and diagnostic basis for judging heart failure clinically, and can also be used for monitoring the efficacy of heart failure treatment. In the diagnosis of acute heart failure, the detection value of 900pg/ml considers heart failure. When the patient has heart failure, it will produce a self protective reaction, leading to the increase of N-terminal pro brain natriuretic peptide to achieve diuresis and reduce cardiac load. The detection value of N-terminal pro brain natriuretic peptide is proportional to the degree of heart failure. When the N-terminal pro brain natriuretic peptide is increased, heart failure is considered. When patients with heart failure are actively treated and their heart failure condition is significantly improved, the corresponding N-terminal pro brain natriuretic peptide detection value will gradually decline, which is commonly used in clinical efficacy monitoring in the treatment of heart failure. Patients with renal dysfunction will also have an increase in N-terminal pro brain natriuretic peptide.