Hepatitis B virus(HBV)

Hepatitis B,referred to as hepatitis B,is a disease caused by hepatitis B virus (HBV) infection. Hepatitis B virus is a hepatotropic virus,which mainly exists in hepatocytes and damages hepatocytes,causing hepatocyte inflammation,necrosis and fibrosis. Hepatitis B is divided into acute and chronic. Acute hepatitis B can heal itself in 90% of adults,while chronic hepatitis B has different manifestations,including chronic hepatitis B carriers,chronic active hepatitis B,hepatitis B cirrhosis,etc.

HBV antigen and antibody detection: surface antigen (HBsAg),surface antibody (anti HBS) е Antigen (HBeAg) е Antibody (anti HBE) and core antibody (anti HBC),known as the five items of hepatitis B,are commonly used detection indicators of HBV infection,which can reflect the level of HBV in the subject and the reaction of the body,and roughly evaluate the level of the virus.HBeAg is a soluble component of hepatitis B core antigen,which often coexists with serum HBVDNA,dna-p and Dane particles,and is a marker of HBV replication and infectivity. Hepatitis B virus e antigen is a soluble protein that exists in the core particle in a concealed form and is distributed in the intercellular space,which may be related to virus replication.

Hepatitis B virus e antigen is the core part of hepatitis B virus,so it is generally considered that hepatitis B virus e antigen positive is a sign of infectious.Hepatitis B virus surface antibody (anti HBS) is an immunoreactive antibody (protective antibody) to hepatitis B surface antigen protein produced by patients after infection with hepatitis B virus. Anti HBS is a neutralizing antibody with protective immunity against HBV,which can neutralize HBV infection and resist reinfection.