Treponema pallidum(TP)

Treponema pallidum is known as Treponema pallidum because it is transparent and not easy to stain. It can be dyed pink with Giemsa. It is a dense spirochete,soft and slender spirochete,shaped like a metal shaving,about 6-12 in length μ m. Width 0.09-0.18 μ m. There are 8-12 neat and uniform helices.

Syphilis antibody detection is divided into non Treponema pallidum antigen serological test and Treponema pallidum antigen serological test.

1、Non Treponema pallidum antigen serological test: mainly including venereal disease research laboratory test (VDRL),unheated serum reagin test (USR),rapid plasma reagin ring card test (RPR) and toluidine red unheated serum test (trust).

2、Treponema pallidum antigen serological test: commonly used mainly include Treponema pallidum particle agglutination test (TPPA),Treponema pallidum hemagglutination test (TPHA),syphilis enzyme-linked immunosorbent assay (ELISA),chemiluminescence immunoassay (CLIA),and syphilis immunochromatography rapid detection of syphilis (RT),fluorescent Treponema antibody absorption test (FTA-ABS),Treponema pallidum western blot test (WB).Tp15,TP17 and TP47 are outer membrane lipoproteins of Treponema pallidum.